Endothelin-1-induced hypertrophic alterations and heme oxygenase-1 expression in cardiomyoblasts are counteracted by beta estradiol: in vitro and in vivo studies

Endothelin-1 (ET-1), a potent vasoconstrictor normally active in maintaining vascular tone, may mediate significant pathogenic effects, contributing to several serious diseases when aberrantly expressed or regulated. The present study evaluates the capacity of ET-1 to affect endothelin-1-associated...

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Veröffentlicht in:Naunyn Schmiedebergs Arch Pharmacol
Hauptverfasser: Barta, Tunde, Tosaki, Agnes, Haines, David, Balla, Gyorgy, Lekli, Istvan, Tosaki, Arpad
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer Berlin Heidelberg 2018
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5851684/
https://ncbi.nlm.nih.gov/pubmed/29354880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00210-018-1462-z
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