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Autophagy: an adaptive physiological countermeasure to cellular senescence and ischaemia/reperfusion‐associated cardiac arrhythmias

Oxidative stress placed on tissues that involved in pathogenesis of a disease activates compensatory metabolic changes, such as DNA damage repair that in turn causes intracellular accumulation of detritus and ‘proteotoxic stress’, leading to emergence of ‘senescent’ cellular phenotypes, which expres...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Lekli, Istvan, Haines, David Donald, Balla, Gyorgy, Tosaki, Arpad
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5431132/
https://ncbi.nlm.nih.gov/pubmed/27997746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13053
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