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Cyclic Strain and Hypertension Increase Osteopontin Expression in the Aorta

Hypertension has a direct impact on vascular hypertrophy and is a known risk factor for the development of atherosclerosis. Osteopontin (OPN) has emerged as an important protein mediator of inflammation and remodeling of large arteries. However, its role and mechanism of regulation in the setting of...

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Detalhes bibliográficos
Publicado no:Cell Mol Bioeng
Main Authors: Caesar, Christa, Lyle, Alicia N., Joseph, Giji, Weiss, Daiana, Alameddine, Fadi M. F., Lassègue, Bernard, Griendling, Kathy K., Taylor, W. Robert
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5851655/
https://ncbi.nlm.nih.gov/pubmed/29552233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12195-016-0475-2
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