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No evidence for association of MTHFR 677C>T and 1298A>C variants with placental DNA methylation
BACKGROUND: 5,10-Methylenetetrahydrofolate reductase (MTHFR) is a key enzyme in one-carbon metabolism that ensures the availability of methyl groups for methylation reactions. Two single-nucleotide polymorphisms (SNPs) in the MTHFR gene, 677C>T and 1298A>C, result in a thermolabile enzyme with...
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| Publicado no: | Clin Epigenetics |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5851070/ https://ncbi.nlm.nih.gov/pubmed/29564022 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-018-0468-1 |
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