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Synthesis of Enantioenriched Allylic Silanes via Nickel-Catalyzed Reductive Cross-Coupling

An asymmetric Ni-catalyzed reductive cross-coupling has been developed to prepare enantioenriched allylic silanes. This enantioselective reductive alkenylation proceeds under mild conditions and exhibits good functional group tolerance. The chiral allylic silanes prepared here undergo a variety of s...

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Publicat a:J Am Chem Soc
Autors principals: Hofstra, Julie L., Cherney, Alan H., Ordner, Ciara M., Reisman, Sarah E.
Format: Artigo
Idioma:Inglês
Publicat: 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5851001/
https://ncbi.nlm.nih.gov/pubmed/29202243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b11707
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