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Inhibition of transcription factor-DNA complexes and gene expression by a microgonotropen
Developing minor groove-binding drugs to selectively inhibit transcription factor (TF)/DNA interactions and accompanying gene expression is a current goal in drug development studies. Equipping minor groove-binding agents with positively charged, major groove-contacting side chains yields microgonot...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The National Academy of Sciences
2001
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC58510/ https://ncbi.nlm.nih.gov/pubmed/11535831 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.191374698 |
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