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Unbiased Estimate of Synonymous and Nonsynonymous Substitution Rates with Nonstationary Base Composition

The measurement of synonymous and nonsynonymous substitution rates (dS and dN) is useful for assessing selection operating on protein sequences or for investigating mutational processes affecting genomes. In particular, the ratio [Formula: see text] is expected to be a good proxy for ω, the ratio of...

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Bibliografske podrobnosti
izdano v:Mol Biol Evol
Main Authors: Guéguen, Laurent, Duret, Laurent
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5850866/
https://ncbi.nlm.nih.gov/pubmed/29220511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msx308
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