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Unbiased Estimate of Synonymous and Nonsynonymous Substitution Rates with Nonstationary Base Composition

The measurement of synonymous and nonsynonymous substitution rates (dS and dN) is useful for assessing selection operating on protein sequences or for investigating mutational processes affecting genomes. In particular, the ratio [Formula: see text] is expected to be a good proxy for ω, the ratio of...

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Detalhes bibliográficos
Publicado no:Mol Biol Evol
Main Authors: Guéguen, Laurent, Duret, Laurent
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5850866/
https://ncbi.nlm.nih.gov/pubmed/29220511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msx308
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