GATA3 zinc finger 2 mutations reprogram the breast cancer transcriptional network

GATA3 is frequently mutated in breast cancer; these mutations are widely presumed to be loss-of function despite a dearth of information regarding their effect on disease course or their mechanistic impact on the breast cancer transcriptional network. Here, we address molecular and clinical features...

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Bibliographic Details
Published in:Nat Commun
Main Authors: Takaku, Motoki, Grimm, Sara A., Roberts, John D., Chrysovergis, Kaliopi, Bennett, Brian D., Myers, Page, Perera, Lalith, Tucker, Charles J., Perou, Charles M., Wade, Paul A.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2018
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5849768/
https://ncbi.nlm.nih.gov/pubmed/29535312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03478-4
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