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Benchmarking common quantification strategies for large-scale phosphoproteomics

Comprehensive mass spectrometry (MS)-based proteomics is now feasible, but reproducible quantification remains challenging, especially for post-translational modifications such as phosphorylation. Here, we compare the most popular quantification techniques for global phosphoproteomics: label-free qu...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Hogrebe, Alexander, von Stechow, Louise, Bekker-Jensen, Dorte B., Weinert, Brian T., Kelstrup, Christian D., Olsen, Jesper V.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5849679/
https://ncbi.nlm.nih.gov/pubmed/29535314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03309-6
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