Nuclear lamina genetic variants, including a truncated LAP2, in twins and siblings with nonalcoholic fatty liver disease

Nonalcoholic fatty liver disease (NAFLD) is becoming the major chronic liver disease in many countries. Its pathogenesis is multifactorial but twin and familial studies indicate significant heritability, which is not fully explained by currently-known genetic susceptibility loci. Notably, mutations...

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Vydáno v:Hepatology
Hlavní autoři: Brady, Graham F., Kwan, Raymond, Ulintz, Peter J., Nguyen, Phirum, Bassirian, Shirin, Basrur, Venkatesha, Nesvizhskii, Alexey I., Loomba, Rohit, Omary, M. Bishr
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5849478/
https://ncbi.nlm.nih.gov/pubmed/28902428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.29522
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