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An Exponential Tilt Mixture Model for Time-to-Event Data to Evaluate Treatment Effect Heterogeneity in Randomized Clinical Trials

Evaluating the effect of a treatment on a time-to-event outcome is the focus of many randomized clinical trials. It is often observed that the treatment effect is heterogeneous, where only a subgroup of the patients may respond to the treatment due to some unknown mechanism such as genetic polymorph...

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Detalles Bibliográficos
Publicado en:Biom Biostat Int J
Main Authors: Wang, Chi, Tan, Zhiqiang, Louis, Thomas A.
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5849265/
https://ncbi.nlm.nih.gov/pubmed/29546253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15406/bbij.2014.01.00006
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