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Discrete mixture modeling to address genetic heterogeneity in time-to-event regression

Motivation: Time-to-event regression models are a critical tool for associating survival time outcomes with molecular data. Despite mounting evidence that genetic subgroups of the same clinical disease exist, little attention has been given to exploring how this heterogeneity affects time-to-event m...

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Bibliografiske detaljer
Main Authors: Eng, Kevin H., Hanlon, Bret M.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4058947/
https://ncbi.nlm.nih.gov/pubmed/24532723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btu065
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