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Discrete mixture modeling to address genetic heterogeneity in time-to-event regression

Motivation: Time-to-event regression models are a critical tool for associating survival time outcomes with molecular data. Despite mounting evidence that genetic subgroups of the same clinical disease exist, little attention has been given to exploring how this heterogeneity affects time-to-event m...

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Detalhes bibliográficos
Main Authors: Eng, Kevin H., Hanlon, Bret M.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4058947/
https://ncbi.nlm.nih.gov/pubmed/24532723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btu065
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