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Pulmonary dendritic cell subsets shape the respiratory syncytial virus-specific CD8(+) T cell immunodominance hierarchy in neonates

Young infants are generally more susceptible to viral infections and experience more severe disease than adults. CD8(+) T cells are important for viral clearance and although often ineffective in neonates can be protective if adequately stimulated. Using a murine CB6F1/J hybrid model of respiratory...

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Détails bibliographiques
Publié dans:J Immunol
Auteurs principaux: Malloy, Allison M.W., Ruckwardt, Tracy J., Morabito, Kaitlyn M., Lau-Kilby, Annie W., Graham, Barney S.
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5849234/
https://ncbi.nlm.nih.gov/pubmed/27895172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1600486
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