A NuRD Complex from Xenopus laevis Eggs Is Essential for DNA Replication during Early Embryogenesis

DNA replication in the embryo of Xenopus laevis changes dramatically at the mid-blastula transition (MBT), with Y RNA-independent random initiation switching to Y RNA-dependent initiation at specific origins. Here, we identify xNuRD, an MTA2-containing assemblage of the nucleosome remodeling and his...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Christov, Christo P., Dingwell, Kevin S., Skehel, Mark, Wilkes, Helen S., Sale, Julian E., Smith, James C., Krude, Torsten
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5848848/
https://ncbi.nlm.nih.gov/pubmed/29490265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.02.015
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