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RepurposeVS: A Drug Repurposing-Focused Computational Method for Accurate Drug-Target Signature Predictions

We describe here RepurposeVS for the reliable prediction of drug-target signatures using X-ray protein crystal structures. RepurposeVS is a virtual screening method that incorporates docking, drug-centric and protein-centric 2D/3D fingerprints with a rigorous mathematical normalization procedure to...

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發表在:Comb Chem High Throughput Screen
Main Authors: Issa, Naiem T., Peters, Oakland J., Byers, Stephen W., Dakshanamurthy, Sivanesan
格式: Artigo
語言:Inglês
出版: 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5848469/
https://ncbi.nlm.nih.gov/pubmed/26234515
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