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Drug Metabolism in Preclinical Drug Development: A Survey of the Discovery Process, Toxicology, and Computational Tools

Increased R & D spending and high failure rates exist in drug development, due in part to inadequate prediction of drug metabolism and its consequences in the human body. Hence, there is a need for computational methods to supplement and complement current biological assessment strategies. In th...

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Foilsithe in:Curr Drug Metab
Main Authors: Issa, Naiem T., Wathieu, Henri, Ojo, Abiola, Byers, Stephen W., Dakshanamurthy, Sivanesan
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5892202/
https://ncbi.nlm.nih.gov/pubmed/28302026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1389200218666170316093301
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