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Wnt signaling promotes hindgut fate commitment through regulating multi-lineage genes during hESC differentiation

Wnt signaling plays essential roles in both embryonic pattern formation and postembryonic tissue homoestasis. High levels of Wnt activity repress foregut identity and facilitate hindgut fate through forming a gradient of Wnt signaling activity along the anterior-posterior axis. Here, we examined the...

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Detalhes bibliográficos
Publicado no:Cell Signal
Main Authors: Zhang, Xiujuan, Chen, Ying, Ye, Ying, Wang, Jianfeng, Wang, Hong, Yuan, Guohong, Lin, Zhe, Wu, Yihui, Zhang, Yan, Lin, Xinhua
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5848428/
https://ncbi.nlm.nih.gov/pubmed/27693749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2016.09.009
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