Synergistic Integration of Mesenchymal Stem Cells and Hydrostatic Pressure in the Expansion and Maintenance of Human Hematopoietic/Progenitor Cells

Ex vivo expansion of hematopoietic stem/progenitor cell (HSPC) has been investigated to improve the clinical outcome of HSPC transplantation. However, ex vivo expansion of HSPCs still faces a major obstacle in that HPSCs tend to differentiate when proliferating. Here, we cocultured HSPCs with mesenc...

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Veröffentlicht in:Stem Cells Int
Hauptverfasser: Kang, Yun Gyeong, Jeong, Jee-Yeong, Lee, Tae-Hee, Lee, Ho Sup, Shin, Jung-Woog
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi 2018
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5848107/
https://ncbi.nlm.nih.gov/pubmed/29681947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/4527929
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