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A KRAS wild type mutational status confers a survival advantage in pancreatic ductal adenocarcinoma

BACKGROUND: The KRAS oncogene is a driver mutation and is present in greater than 90% of pancreatic ductal adenocarcinomas (PDAC). A subset of these tumors, however, do not harbor mutations in KRAS (wild type KRAS). Studies have shown that patients with mutated KRAS have a poorer survival on first-l...

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Dades bibliogràfiques
Publicat a:J Gastrointest Oncol
Autors principals: Windon, Annika L., Loaiza-Bonilla, Arturo, Jensen, Christopher E., Randall, Michael, Morrissette, Jennifer J. D., Shroff, Stuti G.
Format: Artigo
Idioma:Inglês
Publicat: AME Publishing Company 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5848049/
https://ncbi.nlm.nih.gov/pubmed/29564165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/jgo.2017.10.14
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