RSV hijacks cellular protein phosphatase 1 to regulate M2-1 phosphorylation and viral transcription

Respiratory syncytial virus (RSV) RNA synthesis occurs in cytoplasmic inclusion bodies (IBs) in which all the components of the viral RNA polymerase are concentrated. In this work, we show that RSV P protein recruits the essential RSV transcription factor M2-1 to IBs independently of the phosphoryla...

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Veröffentlicht in:PLoS Pathog
Hauptverfasser: Richard, Charles-Adrien, Rincheval, Vincent, Lassoued, Safa, Fix, Jenna, Cardone, Christophe, Esneau, Camille, Nekhai, Sergei, Galloux, Marie, Rameix-Welti, Marie-Anne, Sizun, Christina, Eléouët, Jean-François
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2018
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5847313/
https://ncbi.nlm.nih.gov/pubmed/29489893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006920
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