RSV hijacks cellular protein phosphatase 1 to regulate M2-1 phosphorylation and viral transcription

Respiratory syncytial virus (RSV) RNA synthesis occurs in cytoplasmic inclusion bodies (IBs) in which all the components of the viral RNA polymerase are concentrated. In this work, we show that RSV P protein recruits the essential RSV transcription factor M2-1 to IBs independently of the phosphoryla...

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Publicat a:PLoS Pathog
Autors principals: Richard, Charles-Adrien, Rincheval, Vincent, Lassoued, Safa, Fix, Jenna, Cardone, Christophe, Esneau, Camille, Nekhai, Sergei, Galloux, Marie, Rameix-Welti, Marie-Anne, Sizun, Christina, Eléouët, Jean-François
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2018
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5847313/
https://ncbi.nlm.nih.gov/pubmed/29489893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006920
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