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RSV hijacks cellular protein phosphatase 1 to regulate M2-1 phosphorylation and viral transcription

Respiratory syncytial virus (RSV) RNA synthesis occurs in cytoplasmic inclusion bodies (IBs) in which all the components of the viral RNA polymerase are concentrated. In this work, we show that RSV P protein recruits the essential RSV transcription factor M2-1 to IBs independently of the phosphoryla...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Richard, Charles-Adrien, Rincheval, Vincent, Lassoued, Safa, Fix, Jenna, Cardone, Christophe, Esneau, Camille, Nekhai, Sergei, Galloux, Marie, Rameix-Welti, Marie-Anne, Sizun, Christina, Eléouët, Jean-François
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5847313/
https://ncbi.nlm.nih.gov/pubmed/29489893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006920
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