Transformation of accessible chromatin and 3D nucleome underlies lineage commitment of early T cells

How chromatin reorganization coordinates differentiation and lineage commitment from hematopoietic stem/progenitor cells (HSPC) to mature immune cells has not been well understood. Here, we carried out an integrative analysis of chromatin accessibility, topologically associating domains, AB compartm...

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Vydáno v:Immunity
Hlavní autoři: Hu, Gangqing, Cui1, Kairong, Fang, Difeng, Hirose, Satoshi, Wang, Xun, Wangsa, Darawalee, Jin, Wenfei, Ried, Thomas, Liu, Pentao, Zhu, Jinfang, Rothenberg, Ellen V., Zhao, Keji
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5847274/
https://ncbi.nlm.nih.gov/pubmed/29466755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2018.01.013
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