Specific Labeling of Stem Cell Activity in Human Colorectal Organoids Using an ASCL2-Responsive Minigene

Organoid technology provides the possibility of culturing patient-derived colon tissue and colorectal cancers (CRCs) while maintaining all functional and phenotypic characteristics. Labeling stem cells, especially in normal and benign tumor organoids of human colon, is challenging and therefore limi...

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Detaylı Bibliyografya
Yayımlandı:Cell Rep
Asıl Yazarlar: Oost, Koen C., van Voorthuijsen, Lisa, Fumagalli, Arianna, Lindeboom, Rik G.H., Sprangers, Joep, Omerzu, Manja, Rodriguez-Colman, Maria J., Heinz, Maria C., Verlaan-Klink, Ingrid, Maurice, Madelon M., Burgering, Boudewijn M.T., van Rheenen, Jacco, Vermeulen, Michiel, Snippert, Hugo J.G.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Cell Press 2018
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5847189/
https://ncbi.nlm.nih.gov/pubmed/29425513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.01.033
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