Cardiomyocyte ionic currents in intact young and aged murine Pgc-1β(−/−) atrial preparations

INTRODUCTION: Recent studies reported that energetically deficient murine Pgc-1β(−/−) hearts replicate age-dependent atrial arrhythmic phenotypes associated with their corresponding clinical conditions, implicating action potential (AP) conduction slowing consequent upon reduced AP upstroke rates. M...

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Gepubliceerd in:Mech Ageing Dev
Hoofdauteurs: Valli, Haseeb, Ahmad, Shiraz, Jiang, Anita Y., Smyth, Robert, Jeevaratnam, Kamalan, Matthews, Hugh R., Huang, Christopher L.-H.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier Science Ireland 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5846848/
https://ncbi.nlm.nih.gov/pubmed/29197478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mad.2017.11.016
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