Microenvironment-driven resistance to B-Raf inhibition in a melanoma patient is accompanied by broad changes of gene methylation and expression in distal fibroblasts

The incidence of malignant melanoma is rapidly increasing and current medicine is offering only limited options for treatment of the advanced disease. For B-Raf mutated melanomas, treatment with mutation-specific drug inhibitors may be used. Unfortunately, tumors frequently acquire resistance to the...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:Int J Mol Med
Hoofdauteurs: Kodet, Ondřej, Dvořánková, Barbora, Bendlová, Běla, Sýkorová, Vlasta, Krajsová, Ivana, Štork, Jiří, Kučera, Jan, Szabo, Pavol, Strnad, Hynek, Kolář, Michal, Vlček, Čestmír, Smetana, Karel, Lacina, Lukáš
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: D.A. Spandidos 2018
Onderwerpen:
Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5846633/
https://ncbi.nlm.nih.gov/pubmed/29393387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2018.3448
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items