Prdx1 (peroxiredoxin 1) deficiency reduces cholesterol efflux via impaired macrophage lipophagic flux

Oxidative stress activates macroautophagy/autophagy and contributes to atherogenesis via lipophagic flux, a form of lipid removal by autophagy. However, it is not known exactly how endogenous antioxidant enzymes are involved in lipophagic flux. Here, we demonstrate that the antioxidant PRDX1 (peroxi...

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Vydáno v:Autophagy
Hlavní autoři: Jeong, Se-Jin, Kim, Sinai, Park, Jong-Gil, Jung, In-hyuk, Lee, Mi-Ni, Jeon, Sejin, Kweon, Hyae Yon, Yu, Dae-Yeul, Lee, Sang-Hak, Jang, Yangsoo, Kang, Sang Won, Han, Ki-Hwan, Miller, Yury I., Park, Young Mi, Cheong, Cheolho, Choi, Jae-Hoon, Oh, Goo Taeg
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2017
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5846566/
https://ncbi.nlm.nih.gov/pubmed/28605287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2017.1327942
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