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The glycosylation pathway is required for the secretion of Slit and for the maintenance of the Slit receptor Robo on axons
Slit proteins act as repulsive axon guidance cues by activating receptors of the Roundabout (Robo) family. During early neurogenesis in Drosophila melanogaster, Slit prevents the growth cones of longitudinal tract neurons from inappropriately crossing the midline, thus restricting these cells to tra...
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| Publicado en: | Sci Signal |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5846327/ https://ncbi.nlm.nih.gov/pubmed/28634210 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aam5841 |
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