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The glycosylation pathway is required for the secretion of Slit and for the maintenance of the Slit receptor Robo on axons
Slit proteins act as repulsive axon guidance cues by activating receptors of the Roundabout (Robo) family. During early neurogenesis in Drosophila melanogaster, Slit prevents the growth cones of longitudinal tract neurons from inappropriately crossing the midline, thus restricting these cells to tra...
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| Publicado no: | Sci Signal |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5846327/ https://ncbi.nlm.nih.gov/pubmed/28634210 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aam5841 |
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