A carregar...
Glucose regulates MafA transcription factor abundance and insulin gene expression by inhibiting AMP-activated protein kinase in pancreatic β-cells
Insulin mRNA expression in pancreatic islet β-cells is up-regulated by extracellular glucose concentration, but the underlying mechanism remains incompletely understood. MafA is a transcriptional activator specifically enriched in β-cells that binds to the insulin gene promoter. Its expression is tr...
Na minha lista:
| Publicado no: | J Biol Chem |
|---|---|
| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2018
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5846144/ https://ncbi.nlm.nih.gov/pubmed/29348175 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.817932 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|