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An Inexpensive, In-House-Made, Microdialysis Device for Measuring Drug–Protein Binding

[Image: see text] An inexpensive, in-house made microdialysis device is described that is suitable for measuring the binding of small molecules including drug candidates to serum proteins or other macromolecules. The device is based on the standard equilibrium dialysis method to measure the fraction...

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Detalhes bibliográficos
Publicado no:ACS Med Chem Lett
Main Authors: Herbst, Zackary M., Shibata, Sayaka, Fan, Erkang, Gelb, Michael H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2017
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5846030/
https://ncbi.nlm.nih.gov/pubmed/29541374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.7b00316
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