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Optimal Objective-Based Experimental Design for Uncertain Dynamical Gene Networks with Experimental Error

In systems biology, network models are often used to study interactions among cellular components, a salient aim being to develop drugs and therapeutic mechanisms to change the dynamical behavior of the network to avoid undesirable phenotypes. Owing to limited knowledge, model uncertainty is commonp...

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Bibliografiske detaljer
Udgivet i:IEEE/ACM Trans Comput Biol Bioinform
Main Authors: Mohsenizadeh, Daniel N., Dehghannasiri, Roozbeh, Dougherty, Edward R.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5845823/
https://ncbi.nlm.nih.gov/pubmed/27576263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1109/TCBB.2016.2602873
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