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Specific transcriptional enhancement of inducible nitric oxide synthase by targeted promoter demethylation
The ability to specifically reactivate epigenetically silenced genes would have great utility in experimental studies and potential therapeutic value. Here, we describe the specific targeting of thymidine DNA glycosylase (TDG), an enzyme involved in the mechanism of methylcytosine demethylation, to...
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| 出版年: | Epigenetics |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5845820/ https://ncbi.nlm.nih.gov/pubmed/24008769 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.26267 |
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