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Link between Epigenomic Alterations and Genome-Wide Aberrant Transcriptional Response to Allergen in Dendritic Cells Conveying Maternal Asthma Risk

We investigated the link between epigenome-wide methylation aberrations at birth and genomic transcriptional changes upon allergen sensitization that occur in the neonatal dendritic cells (DC) due to maternal asthma. We previously demonstrated that neonates of asthmatic mothers are born with a funct...

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Bibliographic Details
Main Authors: Mikhaylova, Lyudmila, Zhang, Yiming, Kobzik, Lester, Fedulov, Alexey V.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3741290/
https://ncbi.nlm.nih.gov/pubmed/23950928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0070387
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