Estimating chronic wasting disease susceptibility in cervids using real-time quaking-induced conversion

In mammals, susceptibility to prion infection is primarily modulated by the host’s cellular prion protein (PrP(C)) sequence. In the sheep scrapie model, a graded scale of susceptibility has been established both in vivo and in vitro based on PrP(C) amino acids 136, 154 and 171, leading to global bre...

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Vydáno v:J Gen Virol
Hlavní autoři: Haley, Nicholas J., Rielinger, Rachel, Davenport, Kristen A., O'Rourke, Katherine, Mitchell, Gordon, Richt, Jürgen A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Microbiology Society 2017
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5845664/
https://ncbi.nlm.nih.gov/pubmed/29058651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/jgv.0.000952
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