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Enterococcus faecalis and pathogenic streptococci inactivate daptomycin by releasing phospholipids

Daptomycin is a lipopeptide antibiotic with activity against Gram-positive bacteria. We showed previously that Staphylococcus aureus can survive daptomycin exposure by releasing membrane phospholipids that inactivate the antibiotic. To determine whether other pathogens possess this defence mechanism...

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Pubblicato in:Microbiology (Reading)
Autori principali: Ledger, Elizabeth V. K., Pader, Vera, Edwards, Andrew M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Microbiology Society 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5845577/
https://ncbi.nlm.nih.gov/pubmed/28942757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/mic.0.000529
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