Daptomycin-Resistant Enterococcus faecalis Diverts the Antibiotic Molecule from the Division Septum and Remodels Cell Membrane Phospholipids

Treatment of multidrug-resistant enterococci has become a challenging clinical problem in hospitals around the world due to the lack of reliable therapeutic options. Daptomycin (DAP), a cell membrane-targeting cationic antimicrobial lipopeptide, is the only antibiotic with in vitro bactericidal acti...

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Hlavní autoři: Tran, Truc T., Panesso, Diana, Mishra, Nagendra N., Mileykovskaya, Eugenia, Guan, Ziqianq, Munita, Jose M., Reyes, Jinnethe, Diaz, Lorena, Weinstock, George M., Murray, Barbara E., Shamoo, Yousif, Dowhan, William, Bayer, Arnold S., Arias, Cesar A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Microbiology 2013
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3735187/
https://ncbi.nlm.nih.gov/pubmed/23882013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00281-13
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