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Daptomycin Resistance in Enterococci Is Associated with Distinct Alterations of Cell Membrane Phospholipid Content

BACKGROUND: The lipopeptide antibiotic, daptomycin (DAP) interacts with the bacterial cell membrane (CM). Development of DAP resistance during therapy in a clinical strain of Enterococcus faecalis was associated with mutations in genes encoding enzymes involved in cell envelope homeostasis and phosp...

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Detalhes bibliográficos
Main Authors: Mishra, Nagendra N., Bayer, Arnold S., Tran, Truc T., Shamoo, Yousif, Mileykovskaya, Eugenia, Dowhan, William, Guan, Ziqiang, Arias, Cesar A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3428275/
https://ncbi.nlm.nih.gov/pubmed/22952824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043958
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