Vortioxetine Treatment Reverses Subchronic PCP Treatment-Induced Cognitive Impairments: A Potential Role for Serotonin Receptor-Mediated Regulation of GABA Neurotransmission

Major depressive disorder (MDD) is associated with cognitive impairments that may contribute to poor functional outcomes. Clinical data suggests that the multimodal antidepressant vortioxetine attenuates some cognitive impairments in MDD patients, but the mechanistic basis for these improvements is...

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Dades bibliogràfiques
Publicat a:Front Pharmacol
Autors principals: Pehrson, Alan L., Pedersen, Christian S., Tølbøl, Kirstine Sloth, Sanchez, Connie
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2018
Matèries:
Pharmacology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5845537/
https://ncbi.nlm.nih.gov/pubmed/29559911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00162
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