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Vortioxetine Treatment Reverses Subchronic PCP Treatment-Induced Cognitive Impairments: A Potential Role for Serotonin Receptor-Mediated Regulation of GABA Neurotransmission

Major depressive disorder (MDD) is associated with cognitive impairments that may contribute to poor functional outcomes. Clinical data suggests that the multimodal antidepressant vortioxetine attenuates some cognitive impairments in MDD patients, but the mechanistic basis for these improvements is...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Pehrson, Alan L., Pedersen, Christian S., Tølbøl, Kirstine Sloth, Sanchez, Connie
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5845537/
https://ncbi.nlm.nih.gov/pubmed/29559911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00162
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