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Vortioxetine restores reversal learning impaired by 5-HT depletion or chronic intermittent cold stress in rats

Current treatments for depression, including serotonin-specific reuptake inhibitors (SSRIs), are only partially effective, with a high incidence of residual symptoms, relapse, and treatment resistance. Loss of cognitive flexibility, a component of depression, is associated with dysregulation of the...

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Detalles Bibliográficos
Main Authors: Wallace, Ashley, Pehrson, Alan L., Sánchez, Connie, Morilak, David A.
Formato: Artigo
Idioma:Inglês
Publicado: Cambridge University Press 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4162520/
https://ncbi.nlm.nih.gov/pubmed/24852131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/S1461145714000571
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