Chikungunya Virus Strains Show Lineage-Specific Variations in Virulence and Cross-Protective Ability in Murine and Nonhuman Primate Models

Chikungunya virus (CHIKV) is a reemerging arbovirus capable of causing explosive outbreaks of febrile illness, polyarthritis, and polyarthralgia, inflicting severe morbidity on affected populations. CHIKV can be genetically classified into 3 major lineages: West African (WA); East, Central, and Sout...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Langsjoen, Rose M., Haller, Sherry L., Roy, Chad J., Vinet-Oliphant, Heather, Bergren, Nicholas A., Erasmus, Jesse H., Livengood, Jill A., Powell, Tim D., Weaver, Scott C., Rossi, Shannan L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5844994/
https://ncbi.nlm.nih.gov/pubmed/29511072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02449-17
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