Whole transcriptome profiling of Late-Onset Alzheimer’s Disease patients provides insights into the molecular changes involved in the disease

Alzheimer’s Disease (AD) is the most common cause of dementia affecting the elderly population worldwide. We have performed a comprehensive transcriptome profiling of Late-Onset AD (LOAD) patients using second generation sequencing technologies, identifying 2,064 genes, 47 lncRNAs and 4 miRNAs whose...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Annese, Anita, Manzari, Caterina, Lionetti, Claudia, Picardi, Ernesto, Horner, David S., Chiara, Matteo, Caratozzolo, Mariano Francesco, Tullo, Apollonia, Fosso, Bruno, Pesole, Graziano, D’Erchia, Anna Maria
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5844946/
https://ncbi.nlm.nih.gov/pubmed/29523845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-22701-2
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