Defective regulation of L1 endogenous retroelements in primary Sjogren’s syndrome and systemic lupus erythematosus: Role of methylating enzymes

OBJECTIVE: To investigate whether altered DNA methylation contributes to the inappropriate expression of LINE-1 (L1) retroelements in primary Sjogren’s syndrome (SS) and systemic lupus erythematosus (SLE). METHODS: Minor salivary glands (MSG) were obtained from 42 patients with primary SS [23 withou...

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Bibliographic Details
Published in:J Autoimmun
Main Authors: Mavragani, Clio P., Nezos, Adrianos, Sagalovskiy, Irina, Seshan, Surya, Kirou, Kyriakos A., Crow, Mary K.
Format: Artigo
Language:Inglês
Published: 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5844801/
https://ncbi.nlm.nih.gov/pubmed/29074164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2017.10.004
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