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Long interspersed nuclear element-1 retroelements are expressed in patients with systemic autoimmune disease and induce type I interferon
OBJECTIVE: Increased type I interferon (IFN-I) and a broad signature of IFN-I-induced gene transcripts are observed in patients with SLE and other systemic autoimmune diseases. To identify disease-relevant triggers of the IFN-I pathway we investigated whether endogenous virus-like genomic repeat ele...
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| Publicado no: | Arthritis Rheumatol |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5083133/ https://ncbi.nlm.nih.gov/pubmed/27338297 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.39795 |
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