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Towards discovery and targeted peptide biomarker detection using nanoESI-TIMS-TOF MS

In the present work, the potential of Trapped Ion Mobility Spectrometry coupled to TOF Mass Spectrometry (TIMS-TOF MS) for discovery and targeted monitoring of peptide biomarkers from human-in-mouse xenograft tumor tissue was evaluated. In particular, a TIMS-MS workflow was developed for the detecti...

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Publicat a:J Am Soc Mass Spectrom
Autors principals: Garabedian, Alyssa, Benigni, Paolo, Ramirez, Cesar E., Baker, Erin S., Liu, Tao, Smith, Richard D., Fernandez-Lima, Francisco
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5844780/
https://ncbi.nlm.nih.gov/pubmed/28889248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13361-017-1787-8
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