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The cohort multiple randomized controlled trial design was found to be highly susceptible to low statistical power and internal validity biases

OBJECTIVES: The “cohort multiple randomized controlled trial” (cmRCT) is a recent innovation by which novel interventions are trialed within large longitudinal cohorts of patients to gain efficiencies and align trials more closely to standard clinical practice. The use of cmRCTs is outpacing its met...

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Dades bibliogràfiques
Publicat a:J Clin Epidemiol
Autors principals: Reeves, David, Howells, Kelly, Sidaway, Mark, Blakemore, Amy, Hann, Mark, Panagioti, Maria, Bower, Peter
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5844670/
https://ncbi.nlm.nih.gov/pubmed/29277558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jclinepi.2017.12.008
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