Yeast-based assays for characterization of the functional effects of single nucleotide polymorphisms in human DNA repair genes

DNA repair mechanisms maintain genomic integrity upon exposure to various types of DNA damage, which cause either single- or double-strand breaks in the DNA. Here, we propose a strategy for the functional study of single nucleotide polymorphisms (SNPs) in the human DNA repair genes XPD/ERCC2, RAD18,...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Kim, Changshin, Yang, Jinmo, Jeong, Su-Hyun, Kim, Hayoung, Park, Geun-hee, Shin, Hwa Beom, Ro, MyungJa, Kim, Kyoung-Yeon, Park, YoungJoon, Kim, Keun Pil, Kwack, KyuBum
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2018
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5844570/
https://ncbi.nlm.nih.gov/pubmed/29522548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0193823
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