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Whole-Genome Sequencing of Suppressor DNA Mixtures Identifies Pathways That Compensate for Chromosome Segregation Defects in Schizosaccharomyces pombe

Suppressor screening is a powerful method to identify genes that, when mutated, rescue the temperature sensitivity of the original mutation. Previously, however, identification of suppressor mutations has been technically difficult. Due to the small genome size of Schizosaccharomyces pombe, we devel...

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Detalhes bibliográficos
Publicado no:G3 (Bethesda)
Main Authors: Xu, Xingya, Wang, Li, Yanagida, Mitsuhiro
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5844291/
https://ncbi.nlm.nih.gov/pubmed/29352077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.118.200048
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