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Whole-Genome Sequencing of Suppressor DNA Mixtures Identifies Pathways That Compensate for Chromosome Segregation Defects in Schizosaccharomyces pombe

Suppressor screening is a powerful method to identify genes that, when mutated, rescue the temperature sensitivity of the original mutation. Previously, however, identification of suppressor mutations has been technically difficult. Due to the small genome size of Schizosaccharomyces pombe, we devel...

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Publicado en:G3 (Bethesda)
Autores principales: Xu, Xingya, Wang, Li, Yanagida, Mitsuhiro
Formato: Artigo
Lenguaje:Inglês
Publicado: Genetics Society of America 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5844291/
https://ncbi.nlm.nih.gov/pubmed/29352077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.118.200048
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